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KMID : 0358419920350040562
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Korean Journal of Obstetrics and Gynecology
1992 Volume.35 No. 4 p.562 ~ p.570
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Clinicopathological Correlation in Endometrial Carcinoma
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한병수/Han, B.S
이학희/송준/박찬용/Lee, H.H/song, J./Park, C.Y
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Abstract
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Significant advance in our knowledge of endometrial cancer have occured in the past decade. The incidence of the disease has risen in most western, industrial countries, and better understanding of the pathologic subtypes has evolved the relationship between exogenous estrogen use and endometrial cancer has been well documented.
We have studied clinico pathological correlation of endometrial carcinoma in 20 patients from July, 1975 to June, 1989 at Department of Obstetrics and Gynecology in National Medical Center.
The mean age of endometrial cancer was 52 and mean parity was 2.3
Fifteen cases (75 %) were postmenopausal, 4 cases (20 %) were menopausal and 1 case (5 %) was premenopausal.
Pathologic subtypes were adenocarcinoma (60 %), adenoacanthoma (20 %), papillary adenocarcinoma (10 %) and adenosquamous,cell carcinoma (10 %) in order of frequency.
Abnormal vaginal bleeding was encountered in 90 %, commonly postmenopausal, 75 lower abdominal pain in 15 % and vaginal discharge in 10 %, respectively.
Risk factors were hypertension (20 %), infertility (20,76), obesity (15 %), estrogen use (10 %), diabetes mellitus (5 %) and hyperlipidemia (5 %).
Associated pelvic pathologies were myoma uteri (25 %), adenomyosis (20 %), endometrial hyperplasia (15 %) and ovarian cyst (10 %), respectively. A great number of patient (90 %) was stage lb.
Concordance rate between clinical and surgical stage was 80 %.
Thirteen cases (65 %) were treated by TAH and BSO, 4 cases (20 %) by TAH, BSO with selective lymphadenectomy, 3 cases (15 %) by TAH, BSO with radiation.
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KEYWORD
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